What is Lactobacillus rhamnosus GG?

Lactobacillus rhamnosus GG (often shortened to LGG) is one of the most widely studied probiotic strains worldwide¹. It was first isolated in 1985 by Professors Sherwood Gorbach and Barry Goldin (hence the “GG”), and in 2020 it was reclassified as Lacticaseibacillus rhamnosus GG².

LGG has some distinctive scientific features. For example, it possesses pili, hair-like structures on its surface that help it attach to the gut lining³⁻⁴. This property has been studied as one reason why LGG is able to interact closely with the intestinal environment.

It has been shown to be safe across different age groups, from preterm infants through to older adults, and it is particularly well researched in children⁵. 

Scientific Research: LGG

LGG is one of the most documented probiotics in the world, having been the subject of more than 250 human clinical trials. These studies have investigated its interactions with the gut microbiome and the immune system. Research has also explored its use in contexts such as antibiotic-associated diarrhoea, upper respiratory health, and irritable bowel syndrome (IBS). You can browse a selection of these publications in our research library.

Where You’ll Find It

LGG has been commonly added to certain yoghurts and dairy products. It is also available in some probiotic supplements, either on its own or combined with other strains. However, in multi-strain supplements it is often included at a dose lower than the dose studied in the clinical trials.

At Evidose, we include LGG in our Live Biotic Daily+ formula, at a dose consistent with those used in published research.