The science behind Live Biotic Daily+
Why does the gut microbiome matter?
Trillions of microorganisms live in your gut, and they do far more than help with digestion.
Certain gut bacteria break down dietary fibre to produce short-chain fatty acids, including butyrate. Butyrate fuels the cells lining your colon and helps maintain the gut barrier, which allows nutrients to be absorbed while helping prevent harmful bacteria and unwanted substances from entering the bloodstream.
Your gut microbes also communicate with immune cells, helping your body recognise and respond to potential threats.
They interact with the brain through the gut–brain axis, a two-way communication system involved in mood, stress and behaviour.
Gut bacteria also compete with other microorganisms for space and nutrients, helping prevent potentially harmful microbes from becoming established.
These are just some of the ways your gut microbiome contributes to your health beyond digestion.
Why choose EVIDOSE® Live Biotic Daily+?
+ Extensively researched bacterial strains
Combines four of the world's most researched live bacterial strains: Lactobacillus rhamnosus GG, Bifidobacterium lactis HN019, Lactobacillus acidophilus NCFM and Bifidobacterium lactis DSM 15954. These strains have been investigated in over 500 human clinical trials, including research into digestive comfort, bowel regularity and immune responses.
+ Study-informed doses
Each strain is included at a dose that has been used in human research.
+ 35 billion CFU through shelf life
A full daily serving provides 35 billion CFU. Appropriate overages are built into the formulation so the stated CFU count is maintained through the end of shelf life not just at manufacture.
+ High-strength vitamin D3
Provides 50 µg (2,000 IU) vitamin D3 per full daily serving, a dose supported by the research. Vitamin D contributes to the normal function of the immune system and the maintenance of normal bones and muscle function.
+ Low FODMAP friendly
We deliberately leave out added prebiotic fibres such as inulin and FOS, making Live Biotic Daily+ low-FODMAP friendly and a considered choice for people with sensitive digestion.
+ Flexible daily dosing
Take 1 or 2 capsules daily, depending on your preferred level of support. One capsule provides 17.5 billion CFU, while two provide the full 35 billion CFU daily serving.
The science behind our strains
Discover the clinical research behind each of the friendly bacteria strains in EVIDOSE® Live Biotic Daily+
Lactobacillus rhamnosus GG
Isolated: 1983
Distinctive feature: pili structures help it attach to the gut lining.
Clinical Research: 250+ human trials
Research areas: Antibiotic-associated diarrhoea, digestive health, respiratory health, gut barrier function and immune responses.
Lactobacillus acidophilus NCFM
Isolated: 1970s
Distinctive features: Produces β-galactosidase, an enzyme that breaks down lactose, and has been studied for its interactions with intestinal pain-signalling pathways.
Clinical Research: 60+ human trials
Research areas: Digestive discomfort, irritable bowel syndrome (IBS), lactose metabolism, gut microbiome interactions and immune responses.
Bifidobacterium lactis HN019
Isolated: 1990s
Distinctive feature: Studied in humans for its effects on gut transit time and bowel movement frequency.
Clinical Research: 40+ human trials
Health areas: Gut transit time, bowel regularity, constipation, digestive discomfort and immune responses.
Bifidobacterium lactis DSM 15954
Isolated:1980s
Distinctive feature: Extensive human research on bowel regularity, mucosal immune responses and gut microbiome changes during antibiotic use.
Clinical Research: 200+ human trials
Health areas: Bowel regularity, digestive health, immune responses, respiratory health and gut microbiome composition.
How do live bacterial strains work in the body?
When you take a live bacteria supplement, certain strains survive digestion and reach the intestines, where they interact with your existing gut microbes and intestinal lining.
Depending on the strain, they can attach to intestinal mucus, compete with other microbes, or produce compounds such as acetate and lactate. These compounds can make the gut environment more acidic, making it less favourable for certain potentially harmful bacteria.
They can also be used by other gut bacteria to produce butyrate, a compound that fuels cells lining the colon and helps maintain the gut barrier, which helps prevent harmful substances from entering the bloodstream. This cooperation between microbes is called cross-feeding.
Importantly, live bacteria don't need to settle permanently in your gut to have an effect. They can interact with your existing microbiome as they pass through. Different strains have different properties, which is why the specific strain, dose and human clinical research matter.
Vitamin D supports normal immune function, with receptors found in both immune cells and cells lining the gut. Research has also identified links between vitamin D, the gut microbiome and intestinal barrier function.
Your Daily+ routine
Live Biotic Daily+ is designed to fit into your everyday routine, with flexible dosing to suit your preferences.
+ Take with food: Take two capsules daily with a meal for the full serving of 35 billion live bacteria.
+ Start gradually: If you prefer, begin with one capsule daily for the first four days before increasing to two.
+ Stay consistent: Choose a time that works for you and take it regularly. Everyone's gut microbiome is different, so individual responses can vary. The British Society of Gastroenterology recommends trying a new bacterial product for a minimum of 3 months before reviewing your results.
+ Flexible dosing: Choose one or two capsules daily depending on your preferred level of support. If taking alongside antibiotics, leave at least two hours between doses.
1 capsule = 17.5 Billion CFU, 1000 IU D3
2 capsules = 35 Billion CFU, 2000 IU D3